The African mole-hair has it all figured out.

Not only is it among the animals better adapted to their environment, but also understood (in an evolutionary sense) how to combat aging.
Or rather, this hairless mole has figured out how to get rid of one of the mechanisms that are among the main responsible for aging: the continuous accumulation of proteinaceous material waste that gradually increases and deteriorates in the body, as the tide of junk that accumulates on the shores of New York.
This animal does not exactly graceful managed to devise a way to eliminate all this waste material, allowing them to live longer than its relatives rodents.
So says a study published recently in the journal BBA: Molecular Basis of Disease, which describes a factor at the cellular level that oversees and guides the activities of the proteasome protein complex, one of whose tasks is the chemical decomposition of the remains of proteins.
The proteasome is essentially the sweeper, the garbage truck and the biological incinerator within the body.
The proteins have a crucial role at the cellular level, mediate communication between cells, they function as agents of the immune system because they are structural material of construction, and also function as reserves from an energy point of view.
Imagine that every word you've ever said, every thought you have ever shared was made from a biological jelly blob.
And the more communicated this blob accumulates around you, your every thought is gradually piling on others with a slimy thump in a pile that becomes more and more cumbersome.
Or imagine the mail piles that gradually become larger in the home of a serial accumulator, which in time will gather in the apartment and make movements difficult and prevent the inhabitant of doing even the simplest things, as long as prevent its survival .
Things in this apartment-described cells gradually become slower and more confused.
This apartment-cell could be a part of the nucleus pulposus the center of the backbone of a human body.
More proteins accumulate, not only in a cell but also in those who are close, plus the pulpy material becomes brown and withers because of the sulphurous material.
A study conducted in 2002 estimated that the waste proteins increase on average by 1 percent annually.
The hope of the naked mole life of 31 years, about as much as the average human life expectancy in the early twentieth century.
This longevity has its roots in part in the protein complex of the proteasome, exceptionally robust in the body of hairless moles that are able to tolerate enormous doses of poison.
This resistance is made possible by a special "chaperon transferable containing a cytosolic factor."
This factor essentially is accompanied by proteasomes, and modulates the activity of "scavenger" of the protein.
The proteasome, in the presence of this factor, it is pushed to remain active and is also stimulated to increase production of peptidase materials, i.e. enzymes that have the task of breaking the chemical bonds in certain proteins.
It would be virtually how to bring a mulcher inside the serial accumulator of Example mail before.
The resistance of our friends hairless is greater than average, and includes bizarre coping mechanisms, such as the inability to feel pain, cold-blooded, very low oxygen metabolism rate, a talent unmatched for running both forward and indetro, and teeth much more suitable for digging that for normal functions.
They feed on a combination of their own feces and large tubers (roots) that are underground.
There is a temptation to define this species "ultra-tailored" -just imagine the naked mole in an ecosystem even slightly different from the one in which he lives ...- but it certainly will not be consumed shortly land suitable for their survival .
The good news is that this animal its anti-aging factor can be extracted.
In a more specific language, "the proteasomes of mice, humans and yeast exposed to proteasome impoverished, tiny parts of the cytosol of the naked mole, showing the previously observed inhibition resistance, and the proteasome of mammals also show an increase in activity," explains I study.
Maybe it's time to turn our hairless friends to the secret of immortality (or longevity) than the "technological singularity" Ray.

From Vice